Hepatitis B can be complicated by the diseases?

1. Hepatogenic Diabetes Clinical manifestations and type Ⅱ diabetes, a different point of Hepatogenic diabetes was significantly higher fasting insulin and C-peptide to normal. After the oral glucose insulin and C increased significantly lower than normal peak too. Is because the inactivation of the ability of insulin to reduce the liver to promote increased insulin; another glucagon inactivated in the liver, decreased insulin receptors on liver cells to be reduced, and insulin resistance, elevated blood glucose and therefore insulin although still high; At the same time C-peptide less affected by the liver, so C-peptide is not high, suggesting that the secretion of β-cell function of no obvious abnormalities. Identification with type Ⅱ diabetes mellitus, insulin release test can be used, and C-peptide release test. 2. Fatty Liver The mechanism is not yet clear, characteristic for the general good, single ALT mild to moderate elevated blood lipids increase, B-mode ultrasound examination showed fatty liver waveform, diagnosed according to liver biopsy examination. 3. Cirrhosis of the liver The development of chronic hepatitis, liver cirrhosis, liver fibrosis is the result. The mechanism has not been fully clarified. Is still found in sub-acute, chronic severe hepatitis and the onset of asymptomatic HBsAg carriers hidden. 4. Hepatocellular carcinoma HBV, HCV infection closely associated morbidity. With chronic active hepatitis, cirrhosis, liver cancer are more common occurrence. Also be found in chronic HBV infection for liver cancer without cirrhosis of the liver-stage development. Its mechanism is currently considered the integration of HBV-DNA, in particular the X gene integration. HBxAg trans-activation of proto-oncogene plays an important role. In addition, aflatoxin carcinogenic substances such as certain synergies.